Bioinformatics is the analysis and functional annotation of biological datasets. As the omics fields have developed, they have generated larger and larger quantities of data. This big data cannot be analysed, processed and viewed as text files or even in spreadsheets. To address the complexity and size of data being generated by omics research, the field of bioinformatics emerged. Researchers have developed tools to managing, analysing omics data. These tools are often open source and freely available but have also been bundled into commercial software packaged. While it is possible to learn how to analyse you own data, the process may be very challenging, and it is often best to recruit a dedicated bioinformatician to assist with data management. This portal will undertake to catalogue bioinformatics tool, resources and experts avaialble locally to assist with solving data analysis.
Bioinformatics analysis expecially of NGS data may require a number of step involving different software processing step, conversion of file formats to reach a desired result. In order to prevent needing to re-invent the wheel everytime a analyis needs to be performed, data analysis workflows have been constructed using recognised and accepted software. Furthermore workflow software has been developed to make it easier to construct workflows from existing software
One peptides have been identified and relative protein abundances determined, statistical tests determine which of the protein as significantly differentially expressed between biological conditions and require further study.
High-Performance Computer Clusters
Due to the large volumes and complexity of omics data, it is not always possible to analyse this data on standard desktop computers. Large computer clusters of often required, which are able to store large volumes of data and process data rapidly in parallel. There are a number of local HPC cluster available through academic institutions.
Public cloud computing services are available, where compute resources can be requested on demand.
Bioinformaticians are available to assist you with your project.
The earlier you contact them the more assistance they will be able to offer. In particular, the experimental design is critical in ensuring the success of any project. Contacting a statistician and ensuring your experiment has enough statistical power will go a long way to ensuring its success.
Selecting the best technology for your project will ensure you get the best results for the your project. Omics research is costly, choosing the most appropriate technology for you experiment and budget is therefor critical.
It is best to first run a pilot study and having an expert check the quality of the results before continuing with the bulk of the analysis. The pilot project will also allow you to familiaries yourself with the sample analysis process, the data generated and the means of analysis, before embarking on the main project.
Once you have produced the data, you will realise omics technologies produce mountains of data. It often requires some expertise in handling big data, to deal with the amounts of data produced. Fortunately we have tools and resources to store and process your data making it easy for you to understand. Contact our team of expert bioninformaticians for assistance on all levels of your project.